- What is Rituxan?
- Who is Rituxan for?
- How can Rituxan help people with GPA or MPA?
- How is Rituxan thought to work?
- How is Rituxan given?
- What can I expect with Rituxan infusions?
- Can I take other medicines on the day of my Rituxan infusion?
- What should I know about side effects with Rituxan?
- Are there financial resources to help me get Rituxan therapy?
- Where can I learn more?
Q & A
- Infusion Reactions: Infusion reactions are very common side effects of Rituxan treatment. Serious infusion reactions can happen during your infusion or within 24 hours after your infusion of Rituxan. Your healthcare provider should give you medicines before your infusion of Rituxan to decrease your chance of having a severe infusion reaction
- Severe Skin and Mouth Reactions: Tell your healthcare provider or get medical help right away if you get any of these symptoms at any time during your treatment with Rituxan: painful sores or ulcers on your skin, lips, or in your mouth; blisters; peeling skin; rash; or pustules
- Hepatitis B Virus (HBV) Reactivation: If you have had hepatitis B or are a carrier of hepatitis B virus, receiving Rituxan could cause the virus to become an active infection again. Hepatitis B reactivation may cause serious liver problems, including liver failure and death. You should not receive Rituxan if you have active hepatitis B liver disease. Your healthcare provider will monitor you for hepatitis B infection during and for several months after you stop receiving Rituxan
- Progressive Multifocal Leukoencephalopathy (PML): PML is a rare, serious brain infection caused by a virus that can happen in people who receive Rituxan. People with weakened immune systems can get PML. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML
What are the possible side effects of Rituxan?
Rituxan can cause serious side effects, including:
- Tumor Lysis Syndrome (TLS): TLS is caused by the fast breakdown of cancer cells. TLS can cause you to have kidney failure and the need for dialysis treatment or an abnormal heart rhythm. TLS can happen within 12-24 hours after an infusion of Rituxan. Tell your healthcare provider right away if you have any of the following signs or symptoms of TLS: nausea, vomiting, diarrhea, or lack of energy
- Serious Infections: Serious infections can happen during and after treatment with Rituxan and can lead to death. Rituxan can increase your risk of getting infections and can lower the ability of your immune system to fight infections. People with serious infections should not receive Rituxan
- Heart Problems: Rituxan may cause chest pain, irregular heartbeats, and heart attack. Your healthcare provider may monitor your heart during and after treatment with Rituxan if you have symptoms of heart problems or have a history of heart problems. Tell your healthcare provider right away if you have chest pain or irregular heartbeats during treatment with Rituxan
- Kidney Problems: especially if you are receiving Rituxan for non–Hodgkin’s lymphoma (NHL). Rituxan can cause severe kidney problems that lead to death. Your healthcare provider should do blood tests to check how well your kidneys are working
- Stomach and Serious Bowel Problems That Can Sometimes Lead to Death: Bowel problems, including blockage or tears in the bowel, can happen if you receive Rituxan with chemotherapy medicines. Tell your healthcare provider right away if you have any stomach-area pain during treatment with Rituxan
Your healthcare provider will stop treatment with Rituxan if you have severe, serious, or life-threatening side effects.
What are the most common side effects during treatment with Rituxan?
- Infusion reactions
- Infections (may include fever, chills)
- Body aches
In patients with GPA or MPA, the most common side effects of Rituxan also include:
- Low white and red blood cells
- Muscle spasms
Other side effects include:
- Aching joints during or within hours of receiving an infusion
- More frequent upper respiratory tract infections
These are not all of the possible side effects with Rituxan.
Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at (800) FDA‐1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835‐2555.
Please see the Rituxan Prescribing Information and Medication Guide including Most Serious Side Effects for additional Important Side Effect Information.
|Q.||Are there financial resources to help me get Rituxan therapy?|
|A.||At Genentech, we develop medicines for serious or life-threatening medical conditions. We believe they should be accessible for the patients who need them. Find out about our different programs that may be able to help you get Rituxan treatment.|
|Q.||Where can I learn more?|
|A.||Your doctor is the single most important source of information available to you. If you are looking to learn more about GPA and MPA, you can also visit the Vasculitis Foundation website. The Vasculitis Foundation is a good source of information for people with all types of AAV.|
Call 1-877-317-5179 to talk about your Rituxan treatment.