GPA and MPA Symptoms

The signs and symptoms of GPA (formerly known as Wegener's Granulomatosis) and MPA vary widely. The chart below lists the most common signs and symptoms and the kinds of doctors that you may see. Keep in mind that these are just some of the symptoms of GPA and MPA. There may be others that you are experiencing that are not included in this list.

Be sure to listen to your body

Being aware of your symptoms can help you talk to your doctor about how you're feeling and what treatments may be right for you. You know how you are feeling more than anyone. So if you're not feeling well or you are experiencing symptoms, be sure to talk to your doctor right away.   

It's important to see your doctor regularly so he or she can monitor your disease and any symptoms you may be having.

Common signs and symptoms of GPA and MPA 

These are only some of the signs and symptoms of GPA and MPA. The symptoms of these diseases vary widely, so it's important that you talk to your doctor about any symptoms you may be experiencing. He or she is the only person who can diagnose GPA and MPA.

  Granulomatosis with Polyangiitis Microscopic Polyangiitis
Common signs & symptoms
  • Sinus and nose congestion
  • Nosebleeds
  • Fever
  • Cough (with or without blood)
  • Loss of appetite
  • Weight loss
  • Lack of energy
  • Nasal membrane ulcerations and crusting
  • Hearing loss
  • Eye inflammation
  • Numbness or tingling in limbs
  • Weakness
  • Blood in urine (may or may not change urine color)
  • Joint pain
  • Shortness of breath
  • Cough (with or without blood)
  • Blood in urine (may or may not change urine color)
  • Weight loss
  • Rash and/or skin sores
  • Numbness or tingling in limbs
  • Weakness
  • Fever
Major organs involved
  • Upper respiratory tract (sinuses, nose, ears, and windpipe)
  • Lungs
  • Kidneys
  • Nervous system
  • Skin
  • Kidneys
  • Skin
  • Nervous system
  • Lungs
Types of specialists
  • Dermatologist (a skin specialist)
  • Ear, nose, and throat doctor (ENT)
  • Pulmonologist (a lung specialist)
  • Neurologist (a nervous system specialist)
  • Nephrologist (a kidney specialist)
  • Rheumatologist (a joint and immune specialist)
  • Neurologist (a nervous system specialist)
  • Dermatologist (a skin specialist)
  • Nephrologist (a kidney specialist)
  • Pulmonologist (a lung specialist)
  • Rheumatologist (a joint and immune specialist)

Keep in mind

GPA and MPA affect people of all genders, ages, and races.